Control Balanced Designs Involving Sequences of Treatments

Abstract

Designs involving sequences of treatments for test vs. control comparisons are suitable for research in which each experimental unit receives treatments over time in order to compare several test treatments to one (or more) control treatment(s). These designs can be advantageously used in screening experiments and bioequivalence trials. Three series of such designs are constructed in incomplete sequences wherein the first class of designs is variance balanced while the other two classes of designs are partially variance balanced for test versus test comparisons of both direct and residual effects of treatments.