Comparison of Three Calculation Methods for a Bayesian Inference of P(π1 > π2)

Abstract

In Bayesian inference, some researchers have examined the difference of binominal proportions using θ = P(π₁ > π₂ − Δ₀|X₁,X₂), where X_i denote binomial random variable with parameter π_i. An approximate method and the MCMC method are compared with an exact method for θ, and results of actual clinical trials using θ are presented.